Scientific ASIA

Cello timbres can effectively be used in musical therapy

Music is considered as food to soul and is popular among all age groups around the globe. Different traits of musical sound are known as musical timbre1. They can be similar to viola, cello, violoncello, piano, trumpet as well as human sounds etc. It is well known that musical intonations are utilized dependent on all classical opuses, musical styles as well as musical characters which points out the meaning of musical sentences.

Music possesses variable effect on its listeners which can depend on the theme of the musical compositions played with stringed, wind or keyboard instruments, quality of as well as type of music. However, the effects of auditory musical waves(employed in the musical compositions) have not investigated on the ultra structural level till now. Scientists have studied the impacts of musical intonations on living things particularly on plants (Allium cepa) since several years2.

Accordingly, scientists decided to conduct a new study in order to examine the effects of musical sound from cello, piano as well as trumpet on the skeletal muscle cells by employing electron microscopy and to offer the suitable timbres in the compositions, used for musical therapy3.

For this purpose, research team selected 20 guinea pigs and divided them into four groups with 5 pigs in each group. First group was the control group. While, for ten days, groups 1, 2 and 3 were subjected to Mozart and Vivaldi played with cello, piano and trumpet respectively for 6 hours in a day with 15 min intervals. After 10 days, biopsy materials of skeletal muscle from these pigs were taken and analyzed3.

During this experiment, reversible changes including vacuolization, swelling of mitochondria, strained myofibrils and destruction, amplification of chromatin material, activation of nuclei as well as nucleoli were observed in the piano group. On the other hand, scientists noted permanent and degenerative changes (nuclei with rough chromatin, smashing and loss of nuclei and organelles, smashing of shortened and strained myofibrils) in trumpet group. However, the macromolecules of the muscle cells taken from cello group were usually normal as in the control group.

These results show that cello timbres are similar to human voice as they affect better on skeletal muscle cells. Conclusively, cello timbres can be employed in musical therapy.

Key words: musical sound, musical timbre, classical opuses, auditory musical waves, electron microscopy, guinea pigs, musical therapy, cello timbres


  1. Popova, J., 1958. MusikalnieJanri I formi. MoskovaMuzkiz.
  2. Ekici, N., F. Dane, L. Mamedova, I. Metin and M. Huseyinov, 2007. The effects of different musical elements on root growth and mitosis in onion (Allium cepa) root apical meristem (Musical and biological experimental study). Asian J. Plant Sci., 6: 369-373.
  3. Leyla Mamedova, IsinMetin, NuranEkici, MuradHuseyinov, GularaHuseyinova and Mehmet Kanter, 2007. An Ultrastructural Study on the Effects of Different Musical Timbres on the Skeletal Muscle Cells (Musical, Medical, Biological and Experimental Study). Asian J. Cell Biol., 2: 43-49.

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